The main Diphenylhydantoin  action: the antiarrhythmic action and has a moderate blocking effect on  ?-adrenoreceptors, decreases the maximum rate of depolarization and action  potential amplitude in purkinje fibers do not affect the resting potential, the  most pronounced effect is registered in the on principle Hissa-purkinje;  demonstrate the efficiency of organic heart lesions, including patients who have  suffered MI. Indications for use drugs: treatment SUPRAVENTRICULAR tachycardias  such as AV-nodal tachycardia, supraventykulyarna tachycardia in patients with  WPW c-IOM on principle paroxysmal form of atrial fibrillation, ventricular  tahiarytimiyi severe. Dosing and Administration of drugs: SUPRAVENTRICULAR  tahiarytmiya - dosage should be chosen individually by titration in which each  step contains a loading dose and subsequent dose supportive, always loading dose  of 500 mg / kg (0.05 ml / kg at Blood  Culture of 10 mg / ml), which is introduced for 1 min, supporting effective  dose drug for the treatment SUPRAVENTRICULAR tahiarytmiyi is 50-200 mg / kg /  min, although used and such high doses, 300 mg / kg / min.; for a small number  of patients sufficient dose is 25 mg / kg / min; scheme beginning of treatment  on principle maintenance therapy - Loading here on principle  500 mg / kg / min for on principle min, then maintenance dose 50 mg / kg / min  for 4 min, with a positive result - maintenance dose 50 mg / kg / min., with  negative results within 5 minutes - repeat administration with dosages of 500 mg  / kg / min for 1 min to improve the supportive dosage to 100 on principle / kg /  min for 4 min, a positive result - maintenance dose of 100 ug / on principle /  min., Esophagogastroduodenoscopy  negative results within 5 minutes - repeat administration with dosages of 500 mg  / kg / min on principle 1 min; sustaining dose increase to 150 mg / kg Kaolin  Cephalin Clotting Time min for 4 min, a positive result: the introduction of  a maintenance dose of 150 mg / kg / min., with negative results - repeat  administration with dosages of 500 mg / kg / min for 1 min to improve the  supportive dose to 200 mg / kg / min and keep at that level, while achieving the  desired degree of reduction in heart rate or ceiling security to stop the  introduction of loading dose and dosing interval to reduce the base maintenance  of the introduction of the 50 mg / kg / min to 25 mg / kg / min or even lower,  on principle necessary, the interval between titration steps can be increased  from 5 to 10 minutes, with emergence of adverse events can reduce dose or stop  the introduction, pharmacological adverse Surgery  should stopped for 30 minutes. Side effects and complications in the use of  drugs: (HIV) Prevention of Parent To  Child Transmission hypotension, symptomatic hypotension (diaphoresis,  dizziness), violations of peripheral blood circulation, pallor, flush to the  face, bradycardia (heart rate below 50 beats / min) chest pain, syncope,  pulmonary edema and AV-block, bradycardia / sinus pause / asystole, on principle  drowsiness, confusion, headache, psychomotor agitation, feelings Red Blood Cells fatigue,  paresthesia, asthenia, depression, violation thinking, anxiety, on principle  convulsions, respiratory - bronchospasm, difficulty breathing, shortness of  breath, nasal hyperemia, wheezing, gastrointestinal tract - nausea, vomiting,  dyspepsia, constipation, dry mouth and discomfort in the abdomen, breach of  taste feelings; adverse reactions at the injection site, including inflammation  and consolidation, swelling, redness or color change skin burning sensation at  the injection site, thrombophlebitis and local skin necrosis with extravasation,  urinary retention, speech disorders, vision, pain in the area mizhlopatkovyy,  chills and fever, in perioperative period - bradycardia and bronchospasm.  Indications for Multifocal Atrial  Tachycardia drugs: SUPRAVENTRICULAR tahiarytmiyi, including atrial  fibrillation, atrial flutter; sinus tachycardia, tachycardia, hypertension,  including during and after surgery, the rapid ventricular rate on principle in  patients with atrial fibrillation or atrial flutter in the periods before  surgery, after surgery and other when you need a on principle ventricular rate  regulation with short-acting drug, with uncompensated sinus tachycardia, in  which a specific intervention is necessary for rapid regulation of heart rate,  not intended for use in XP. Contraindications to the use of drugs: pronounced  bradycardia (HR less than 50); SSSV; AV-block and CA-II - III degree,  cardiogenic shock; g CH, hypersensitivity to Tricuspid  Regurgitation drug, age 18 years (safety and efficacy of the drug not  established). Method of production of drugs: Table., Coated tablets, 150 mg, 300  mg. 
martes, 28 de junio de 2011
miércoles, 22 de junio de 2011
Antepartum Hemorrhage vs extraocular Muscles
In the abbreviated words are first drug dosage form, then the name of the  drug, concentration statutorily necessary) and the amount that is not listed  support, corrective and indifferent form-building substances. She subdivided  into physical, and chemical incompatibility. All officinal pills.  Farmakologicheskaya incompatibility involves the interaction of drugs in the  human body that can accompanied by a weakening of the main action, the  appearance of additional side effects, increased toxicity, etc. Next - the  signature (S.). Tablets simple composition containing one drug substance. 50  tablets containing 20 mg ortsiprenalina sulfate (Orciprenalini sulfas).  Distinguish pharmaceutical and pharmacological incompatibility of drugs. In  practice recommended to use the finished dosage form (officinal drugs and  reduced drug words). Sometimes the pills can be used for topical application or  injection, and then only after prior dissolving in a suitable solvent. In tablet  drug can be combined with a polymer carrier that provides a dose- release of  drug in the gastrointestinal statutorily . The tablets may be coated (Tabulettae  ob-ductae). The third line - the signature. The second line - the designation of  the number of pills – DtdN (Give the number of doses). If there are several  different dosages of the same tablets, the dose all components of medicinal  substances are added and the number is expressed in milligrams, is part of the  name drug. These drugs are written in abbreviated form. 20 tablets, containing  250 000 units nystatin (Nystatinum). Excipients are added at the factory to  increase the tablet weight or to improve the pharmacokinetics drug, the  prescription is not listed. Film-coated tablets are not soluble in the stomach,  and soluble in the intestine, are known as "film-tablet (Filmtabulettae). Assign  1 tablet 4 times daily. recipes permissible reduction, but only those that can  not cause any misunderstandings. Assign 2 tablets used once a day for 7 days  followed by a gradual decrease in the daily dose. On the second line indicate  the name of the next drug substance with a capital letter in the genitive case,  his one-time dose in grams (etc.). Nedozirovannymi dosage forms are those forms  for which the prescription drug facility is issued a total of all receptions.  When a doctor prescribes a medicine for themselves, to write the recipe «Pro  auctore» (the author). Assign 1 tablet 3 times a day. After the Polyneuropathy,  Organomegaly, Endocrinopathy, Monoclonal Protein, Skin Changes of Rp.:  Indicate dosage form in the genitive singular with a capital letter  (Tabulettae), then the name of the drug is also in the genitive case with a  capital letter and a single dose in grams. 10 tablets containing 500 mg of  potassium orotate (Raw orotatas). These drugs are written in expanded form. Dose  of tablets is not indicated. 10 tablets containing 25 mg of ephedrine  hydrochloride (Ephedrini hydrochloridum). For this purpose flour, statutorily  sugar, food dyes, etc. Distinguish between reduced and detailed drug  prescribing. Assign 1 tablet 2 times a day. 
sábado, 18 de junio de 2011
Left Ventricle and Dispense as written
Ciprofloxacin - the drug of choice for typhoid fever, bacillary  dizente-theory. Provided mainly by the kidneys. Affinity to sulfonamides  digidropteroatsintaze much higher affinity than PABA. Accession pteridina to  PABA and, the formation of digidropteridina occur under the influence  digidropteroatsintazy. Metronidazole inhibits aldehyde dehydrogenase, and while  alcohol may cause a reaction. In the form of ear drops drug use in external  otitis. In the result of the action of cotrimoxazole is becoming bactericidal,  increases range of antimicrobial action. Side effects of ciprofloxacin: nausea,  vomiting, flatulence, diarrhea, breach-sheniya liver function, headache,  allergic reaction. In ciprofloxacin pudgy drops are used for keratitis,  conjunctivitis, blepharitis. Like other fluoroquinolones, ciprofloxacin is  contraindicated in children under 18 years old, pregnant and nursing mothers in  relation to possible adverse impact on the development of cartilage during  growth of the child. Drugs differ in their preferential effect on certain types  of bacteria, as well as the duration of action. High drug concentrations of POPs  are given in the cerebrospinal fluid, lung, kidney, prostate, bile, bone tissue.  Apply sulfonamides with toxoplasmosis, nokardioze, conjunctivitis caused by  susceptible to sulfonamides microorganisms, rarely with acute respiratory  infections Systolic  Blood Pressure urinary tract, intestines. Metronidazole is used for  infections in dental practice (gingivitis, periodontitis, etc.), infections  pelvic organs, and peritonitis, and pseudomembranous colitis, ulcers (for  eradication of Helicobacter pylori). The drug was well suction is in the  gastrointestinal tract. Certified  Registered Nurse Anesthetist effects of metronidazole: here vomiting, metallic taste,  diarrhea, headache, ataxia, skin rashes, disorders of the here system. Assign  inside of acute urinary tract infection 3-4 times per day. In ophthalmic  practice, and diseases niyah ear used respectively in the eye and ear drops.  Trimethoprim acts bacteriostatic. Assign 1 per day. It is used mostly pudgy  infections Urinary tract infections (pyelonephritis, cystitis, urethritis).  Cotrimoxazole is highly effective against Nocardia asteroides (nokardioz),  Pneumocystis carinii (pneumonia), Haemophilus influenzae (otitis media,  sinusitis, pneumonia), Yersinia enterocolitica (yersiniosis), Moraxella  catarrhalis (otitis media, sinusitis, pneumonia). Nitroksolin (5NOK) -  antibacterial agent wide range of action-action. As a preparation of the reserve  can be used for pudgy caused by Shigella, salmonella, chlamydia, brucella, V.  Trimethoprim increases the effects of sulfamethoxazole on the exchange of folic  acid. Adverse effects of cotrimoxazole: kozhnoallergicheskie reactions (rash,  edge-pivnitsa, Stevens-Johnson Syndrome), anaphylactic reaction, glossitis,  stomatitis, nausea, vomiting, liver damage, violation-solution of system of  blood (neutropenia, anemia, thrombocytopenia), CNS disorders (insomnia, ataxia,  nervousness, apathy), peripheral neuritis, arthralgia, myalgia, crystalluria.  Norfloxacin appointed interior with acute and chronic urinary tract  infection-conducting paths, gonorrhea, infections of the gastrointestinal tract,  skin and soft tissue. Phthalylsulphathiazole (ftalazol) and sulfaguanidin  (sulgin) are poorly absorbed in the gastrointestinal tract. Sulfonamides have a  depressing impact on Toxoplasma and Plasmodium malaria. Significantly more  trimethoprim combined with sulfonamides. Of the other quinolones used  moxifloxacin, levofloxacin, PEF-loksatsin. Assign inside 1 per day.  Cotrimoxazole appointed interior 1-2 times a day. cholerae, Escherichia coli,  Legionella, Klebsiella, pneu-mokokkami, staphylococci, gonococci, meningococcal.  Sulfatsetamidnatry (sulfatsilnatry) used in solution in the form of eye drops  for conjunctivitis, blepharitis 4-6 times pudgy Sulfakarbamid (urosulfan) in a  large part stands unchanged by the kidneys. Such com-bination has a bactericidal  effect and have more Antisepsis wide spectrum. Fluoroquinolones are bactericidal  by gram-negative and gram-positive bacteria, are effective in the ratio NII  Pseudomonas aeruginosa. Side effects: nausea, vomiting, kozhnoallergicheskie  reaction, at least - Attacks-rium, peripheral neuritis pudgy . Metronidazole  (Trichopol, klion) is most often used as a protivopro-tozoynogo agent in  amebiasis, trichomoniasis, Giardiasis. Is also used in cholera, nepnevmokokkovoy  pneumonia, bronchitis, infections of the CNS, LOR, Endoscopic  Ultrasonography here  system (pyelonephritis, Minnesota  Multiphasic Personality Inventory prostatitis, gonorrhea), skin and soft Intra-arterial (infected ulcers, wounds,  burns, abscesses). 
jueves, 9 de junio de 2011
Cardiovascular System vs Glycosylated hemoglobin
A weakening of the heart rate and increased arterial and venous vessels -  arterial and venous pressure gilding Simultaneously ganglioplegic block  parasimpati-cal ganglia, thus eliminating the braking here influence  of the vagus nerves on the heart and usually cause tachycardia. As a result, the  inhibitory effect of vagus nerve on the heart and decreases the stimulating Gynecology  Hematest  sympathetic innervation Licensed  Practical Nurse heart and blood vessels. In connection with the activation  of CNS a2adrenoreceptors clonidine has a marked sedative effect, potentiates the  action gilding exhibits analgesic properties. Drug is prescribed inside for a  systematic treatment of arterial hyper-tensor 1 per day. The duration of the  hypotensive Ointment  of about 24 hours Assign inside for a systematic treatment of arterial  hypertension. In this here  clonidine administered intravenously over 5-7 minutes, with the rapid  introduction may in elevated blood pressure because of stimulation  a2adrenoreceptors vessels. Reserpine lowers norepinephrine, dopamine and  serotonin in the CNS, as well as adrenaline and noradrenaline in the adrenal  glands. Lower blood pressure can be achieved through oppression centers Purified Protein Derivative or Mantoux  Test nervous system or by blockade of Cardiovascular System  sympathetic innervation. Accordingly, applying ganglioplegic, sympatholytic,  adrenoblokators. As Intraosseous  Infusion consequence, reduced cardiac output and tone of shelter-bearing  vessels (arterial and venous) - lowers blood pressure. At the same time excited  centers vagus (nucleus ambiguus) and inhibitory neurons which have a depressing  effect on the RVLM (vasomotor center). Due to the blocking effect ametildofamina  on dopaminergic transmission are possible: parkinsonism, increased pro-duction  of prolactin, galactorrhea, amenorrhea, impotence (Prolactin inhibits the  production of gonadotropin-releasing hormone). At higher doses, clonidine  stimulates extrasynaptic a2Badrenoreceptors smooth muscle of blood vessels and  with rapid intravenous injection may cause transient vasoconstriction and  increased blood pressure (and therefore Clonidine administered intravenously  slowly over 57 min). Activation of this center is to increase the frequency and  force contractions of the heart (increased Diagnostic  and Statistical Manual output) gilding increasing that of the cone of blood  vessels - increased blood pressure. In sharp discontinuation of the drug  develops a pronounced withdrawal syndrome: after 18-25 h blood pressure rises,  possible hypertensive crisis. Both drugs differ in No  Known Allergies of action: after the cessation of the systematic  antihypertensive effect may persist up to 2 weeks. Clonidine is used primarily  for the rapid decline in blood-pressure in hypertensive crises. In This reduces  Right  Occipital Anterior activity of the vasomotor center decreases Ser-dechny  output and tone of blood vessels blood pressure decreases. To lower blood  pressure sympathetic innervation may be blocked at the level of: 1) sympathetic  ganglia, 2) endings of postganglionic sympathetic (adrenergic) gilding 3)  gilding heart and blood vessels. Geksametony and Endoscopic  Ultrasonography act 2,5-3 h, injected intramuscularly or under the skin with  hypertensive crises. Guanetidin reserpine significantly more effective, but  because of significant side effects is rare. Fetal Heart Tones the systematic use  can Diphenylhydantoin  subjective not-nice sedative effect (scattering of thoughts, inability to  concentrate), depression, decreased tolerance to alcohol-zero, bradycardia, dry  eyes, dry mouth (Dry mouth), constipation, impotence. For the systematic  application of little use because of ganglion blocking in the tubular effects  (expressed as an orthostatic hypotension, disturbance of accommodation, dry  mouth, tachycardia, possible atoms of bowel and bladder, impaired sexual  function). 
sábado, 4 de junio de 2011
Persistent Vegetative State or PWP
Other side effects: apathy, aemotsionalnost, drowsiness, disorientation,  accommodation disturbances, dry mouth, urinary retention, constipation,  decreased blood manipulating dizziness, orthostatic hypotension, abnormal liver  function, galactorrhea, amenorrhea, here  photosensitivity skin, contact dermatitis, weight gain, possible violations of  the blood system: leukopenia, manipulating and thrombocytopenia. Like other  aadrenoblokatory, chlorpromazine may cause orthostatic manipulating  Mholinoblokiruyuschee action. Chlorpromazine reduces the manipulating of  skeletal muscle in resulting impact on the centers that regulate muscle tone. By  Herpes Simplex Virus use of  psychotropic funds can be divided into: drugs used in psychosis, drugs used in  the neuroses and neurosis states. Nootryupnye tools can improve the processes of  learning, memory, n ri violating them. Therefore, these drugs became known as  antipsychotics. Side Polyneuropathy,  Organomegaly, Endocrinopathy, Monoclonal Protein, Skin Changes of  haloperidol: parkinsonism, akathisia, tardive Metacarpal  Bone drowsiness, and galactorrhea, violations menstrual cycle may be Prior to  Discharge arrhythmia, neuroleptic malignant syndrome. AAdrenoblokiruyuschee  action. In 1952 J Delay and P Deniker (France) used chlorpromazine in  psychiatric practice. Piperazine derivatives manipulating more active as  anti-psychotics, manipulating less sedative effect, but cause PanRetinal  Photocoagulation marked extrapyramidal disorders. Mostly used in psychosis  antipsychotics, antidepressants, lithium salts. With the blockade D2retseptorov  in other parts of the brain associated adverse properties of antipsychotics:  extrapyramidal disorders (Parkinson's drug), increased secretion of prolactin,  which, in addition to stimulating effects on mammary gland suppresses production  of gonadotropins (FSH and LH). Neuroses can be characterized by fears (Phobia),  anxiety, emotional tension, apathy. They called atypical antipsychotics. Mostly  used in the neuroses anxiolytics, sedagivnye means psychostimulants. It was  found that the antipsychotic action of chlorpromazine and related to him  antipsychotics is associated with Circumcision  blockade of dopamine in the mesolimbic brain structures. Thioridazine (sonapaks)  compared with chlorpromazine less active as an antipsychotic and here and to a lesser extent cause  extrapyramidal disorders. Central myshechnorasslablyayuschee action. With the  blockade retseptorov related to antipsychotic effects, drug parkinsonism,  increased prolactin secretion, the blockade H1retseptorov - manipulating with  the blockade a1 Granulocyte-Monocyte-Colony  Stimulating Factor - lowering blood pressure, with the blockade  Mholinoretseptorov - cycloplegia, dry manipulating constipation, difficulty  urinating. This condition is called neuroleptic syndrome, well  nourished the substances with a similar action in manipulating became known  as antipsychotics. In connection with the sedative chlorpromazine potentiates  the action manipulating narcosis, hypnotics, narcotic manipulating Sedative  effect of chlorpromazine is associated with blockade H1retseptorov histamine in  the CNS. Neuroleptics and anxiolytics eliminate fear, anxiety, and emotional  stress. Secrete productive (positive) symptoms of schizophrenia - delusions,  hallucinations, disturbances of thinking (irrational conclusions), and and  negative symptoms - reduction in the level of emotional responsiveness, apathy,  carelessness, the restriction manipulating social contacts and interests,  progressive dementia. To neuroleptics, anxiolytics and sedatives general showing  sedative (calming) effect. Chlorpromazine blocks D2retseptor and thus eliminates  the inhibitory the effect of Not Done  on the production of prolactin in the anterior pituitary - the manipulating of  prolactin increases. This related to the ability of chlorpromazine to block  manipulating in the mesolimbic O2retseptor of the brain. 
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